Vayne ADC is ranked S+ Tier and has a 52.13% win rate in LoL Patch 7.24. We've analyzed 3217 Vayne ADC games to compile our statistical Vayne Build Guide. For items, our build recommends: Berserker's Greaves, Statikk Shiv, Infinity Edge, Blade of the Ruined King, Rapid Firecannon, and Phantom Dancer. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and <pathBonus><pathPrecision>Precision</pathPrecision> + <pathDomination>Domination</pathDomination> </pathBonus> (Secondary). The optimal Summoner Spells for this build are Flash and Heal. Starting items should include Health Potion, Doran's Blade, Doran's Shield, Cull, and Warding Totem (Trinket). Vayne's Best ADC matchups include Kalista, Corki, and Quinn. Vayne's Best ADC counters are Sivir, Miss Fortune, and Twitch.
Vayne Summoner Spells
Vayne Starting Items
Vayne Runes
Vayne Items
Vayne Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Vayne Trinkets
Vayne Boots
Average Support Duo Queue Champions for Vayne ADC(49% - 51% win rate with Vayne)
Even ADC Matchups for Vayne ADC(49% - 51% win rate for Vayne)
Even Support Matchups for Vayne ADC(49% - 51% win rate for Vayne)
