Tier: AWin52.44%Role10.80%Pick0.10%Ban0.31%Games: 82KDA: 2.34Score: 53.43
Karthus ADC is ranked A Tier and has a 52.44% win rate in LoL Patch 25.10. We've analyzed 82 Karthus ADC games to compile our statistical Karthus Build Guide. For items, our build recommends: Blackfire Torch, Malignance, Sorcerer's Shoes, Liandry's Torment, Rylai's Crystal Scepter, and Shadowflame. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Exhaust and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best ADC matchups include Caitlyn, Senna, and Varus. Karthus's Best ADC counters are Jhin, Lucian, and Kai'Sa.
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Karthus Summoner Spells


Win %
Pick %
53%
88%
54%
59%

50%
46%

100%
2%

33%
4%

0%
1%
Karthus Starting Items
Win %
Buy %


2

55%
38%


3
50%
2%
Karthus Runes
Win %
Pick %
59%
50%
46%
40%
50%
5%
0%
1%
Karthus Items

59%

50%

53%

50%

61%

52%

52%

25%
Karthus Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Karthus Item Purchase Order

























Karthus Trinkets
Win %
Buy %

52%
91%

45%
35%

60%
6%
Karthus Boots
Win %
Buy %

53%
91%

100%
1%
Karthus Situational Items
Win %
Buy %

54%
16%

44%
11%

60%
6%

38%
10%

100%
2%

50%
2%