Lissandra Mid Lane is ranked B Tier and has a 50.00% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 296 Lissandra Mid Lane games to compile our statistical Lissandra Spellbook Build Guide. For items, our build recommends: Luden's Companion, Malignance, Sorcerer's Shoes, Shadowflame, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Placeholder. Starting items should include Amplifying Tome, Doran's Ring, Health Potion, and Stealth Ward. Lissandra's Best Spellbook Mid Lane matchups include Katarina, Gragas, and Xerath. Lissandra's Best Spellbook Mid Lane counters are LeBlanc, Sylas, and Aurora.
Lissandra Summoner Spells




Lissandra Starting Items








Lissandra Runes
Lissandra Items








Lissandra Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Lissandra Item Purchase Order
























Lissandra Ultimate Spellbook Stats
























































































Lissandra Trinkets



Lissandra Boots






Lissandra Situational Items





