Tier: SWin56.35%Role72.57%Pick4.95%Games: 1008KDA: 2.12Score: 59.54
Vayne ADC is ranked S Tier and has a 56.35% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 1008 Vayne ADC games to compile our statistical Vayne Spellbook Build Guide. For items, our build recommends: Berserker's Greaves, Blade of The Ruined King, Kraken Slayer, Guinsoo's Rageblade, Wit's End, and Terminus. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Resolve (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Doran's Blade, Long Sword, Health Potion, and Stealth Ward. Vayne's Best Spellbook ADC matchups include Brand, Ezreal, and Heimerdinger. Vayne's Best Spellbook ADC counters are Karthus, Malzahar, and Aphelios.
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Vayne Summoner Spells


Win %
Pick %
56%
99%
56%
96%

64%
4%

82%
1%

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0%

100%
0%
Vayne Starting Items
Win %
Buy %



3

62%
16%



64%
6%
Vayne Runes
Win %
Pick %
59%
61%
55%
17%
58%
3%
58%
1%
Vayne Items

57%

56%

57%

58%

62%

61%

56%

58%
Vayne Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Vayne Item Purchase Order



























Vayne Ultimate Spellbook Stats

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1%

0%

7%

11%

21%

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Vayne Trinkets
Win %
Buy %

56%
76%

57%
44%

57%
9%
Vayne Boots
Win %
Buy %

57%
91%

66%
17%

59%
6%

70%
4%

58%
3%

50%
0%
Vayne Situational Items
Win %
Buy %

66%
21%

62%
14%

57%
15%

61%
14%

62%
13%

70%
10%