Karthus Mid Lane is ranked A Tier and has a 40.87% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 80 Karthus Mid Lane games to compile our statistical Karthus Spellbook Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Rabadon's Deathcap, Shadowflame, and Void Staff. For runes, the strongest choice is Inspiration (Primary) with First Strike (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Doran's Ring, Health Potion, and Stealth Ward. Karthus's Best Spellbook Mid Lane matchups include Akshan, Katarina, and Vex. Karthus's Best Spellbook Mid Lane counters are Corki and Zed.
Karthus Summoner Spells
Karthus Starting Items
Karthus Runes
Karthus Items
Karthus Skill Order
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