Kai'Sa Mid Lane is ranked Off Meta Tier and has a 39.69% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 208 Kai'Sa Mid Lane games to compile our statistical Kai'Sa Spellbook Build Guide. For items, our build recommends: Statikk Shiv, Manamune, Berserker's Greaves, Guinsoo's Rageblade, Nashor's Tooth, and Shadowflame. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Doran's Blade, Long Sword, Health Potion, and Stealth Ward. Kai'Sa's Best Spellbook Mid Lane matchups include Fizz, Galio, and Swain. Kai'Sa's Best Spellbook Mid Lane counters are Caitlyn, Diana, and Naafiri.
Kai'Sa Summoner Spells
Kai'Sa Starting Items
Kai'Sa Runes
Kai'Sa Items
Kai'Sa Skill Order
 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Q | Q | Q | Q | Q | |||||||||||||
 | W | W | W | W | W | |||||||||||||
 | E | E | E | E | E | |||||||||||||
 | R | R | R |
Kai'Sa Item Purchase Order
2900
29001100
3000
3000
3200Kai'Sa Ultimate Spellbook Stats
Kai'Sa Trinkets
Kai'Sa Boots
Kai'Sa Situational Items
Average Jungle Duo Queue Champions for Kai'Sa Mid Lane in Ultimate Spellbook(49% - 51% win rate with Kai'Sa)
Even Mid Lane Matchups for Kai'Sa Mid Lane in Ultimate Spellbook(49% - 51% win rate for Kai'Sa)
