Karma Mid Lane is ranked Off Meta Tier and has a 47.95% win rate in LoL Patch 13.23. We've analyzed 12254 Karma Mid Lane games to compile our statistical Karma Build Guide. For items, our build recommends: Ionian Boots of Lucidity, Luden's Tempest, Imperial Mandate, Shadowflame, Cosmic Drive, and Zhonya's Hourglass. For runes, the strongest choice is Sorcery (Primary) with Arcane Comet (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Flash and Teleport. Starting items should include Doran's Ring, Health Potion, and Stealth Ward. Karma's Best Mid Lane matchups include Sion, Cho'Gath, and Kayle. Karma's Best Mid Lane counters are Kennen, Swain, and Gragas.