Nocturne Mid Lane is ranked Off Meta Tier and has a 38.90% win rate in LoL Patch 13.23. We've analyzed 3251 Nocturne Mid Lane games to compile our statistical Nocturne Build Guide. For items, our build recommends: Duskblade of Draktharr, Mercury's Treads, Ravenous Hydra, Axiom Arc, Prowler's Claw, and Black Cleaver. For runes, the strongest choice is Precision (Primary) with Lethal Tempo (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Flash and Ignite. Starting items should include Doran's Blade, Health Potion, and Stealth Ward. Nocturne's Best Mid Lane matchups include Diana, Annie, and Zoe. Nocturne's Best Mid Lane counters are Ekko, Cho'Gath, and Akshan.