Cassiopeia Lane is ranked A Tier and has a 54.33% win rate in LoL Nexus Blitz Patch 13.23. We've analyzed 5642 Cassiopeia Lane games to compile our statistical Cassiopeia Nexus Blitz Build Guide. For items, our build recommends: Liandry's Anguish, Archangel's Staff, Rylai's Crystal Scepter, Demonic Embrace, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Precision (Primary) with Conqueror (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Flash and Ghost. Starting items should include Tear of the Goddess, Health Potion, and Stealth Ward. Cassiopeia's Best Nexus Blitz Lane matchups include Wukong, Kennen, and Udyr. Cassiopeia's Best Nexus Blitz Lane counters are Ivern, Sona, and Sejuani.