Kai'Sa Top Lane is ranked Off Meta Tier and has a 48.27% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 2543 Kai'Sa Top Lane games to compile our statistical Kai'Sa Spellbook Build Guide. For items, our build recommends: Berserker's Greaves, Kraken Slayer, Manamune, The Collector, Nashor's Tooth, and Phantom Dancer. For runes, the strongest choice is Domination (Primary) with Hail of Blades (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Tear of the Goddess, Long Sword, Refillable Potion, and Stealth Ward. Kai'Sa's Best Spellbook Top Lane matchups include Gnar, Sion, and Illaoi. Kai'Sa's Best Spellbook Top Lane counters are Akshan, Fiora, and Yorick.