Seraphine Support is ranked S Tier and has a 51.58% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 45390 Seraphine Support games to compile our statistical Seraphine Spellbook Build Guide. For items, our build recommends: Luden's Tempest, Sorcerer's Shoes, Chemtech Putrifier, Rylai's Crystal Scepter, Zhonya's Hourglass, and Shard of True Ice. For runes, the strongest choice is Sorcery (Primary) with Summon Aery (Keystone), and Inspiration (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Spellthief's Edge, Health Potion, and Stealth Ward. Seraphine's Best Spellbook Support matchups include Kennen, Syndra, and Zoe. Seraphine's Best Spellbook Support counters are Taliyah, Sejuani, and Nidalee.