Cassiopeia Support is ranked Off Meta Tier and has a 45.01% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 1133 Cassiopeia Support games to compile our statistical Cassiopeia Spellbook Build Guide. For items, our build recommends: Liandry's Anguish, Archangel's Staff, Zhonya's Hourglass, Demonic Embrace, Rylai's Crystal Scepter, and Shard of True Ice. For runes, the strongest choice is Precision (Primary) with Conqueror (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Tear of the Goddess, Spellthief's Edge, Refillable Potion, and Stealth Ward. Cassiopeia's Best Spellbook Support matchups include Maokai, Ashe, and Cho'Gath. Cassiopeia's Best Spellbook Support counters are Nautilus, Fiddlesticks, and Malphite.