Karthus Mid Lane is ranked C Tier and has a 44.31% win rate in LoL Ultimate Spellbook Patch 14.19. We've analyzed 2392 Karthus Mid Lane games to compile our statistical Karthus Spellbook Build Guide. For items, our build recommends: Malignance, Sorcerer's Shoes, Blackfire Torch, Liandry's Torment, Shadowflame, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Dark Harvest (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Sapphire Crystal, and Glowing Mote. Karthus's Best Spellbook Mid Lane matchups include Ezreal, Ziggs, and Aurelion Sol. Karthus's Best Spellbook Mid Lane counters are Viktor, Brand, and Heimerdinger.
Karthus Summoner Spells
Karthus Starting Items
Karthus Runes
Karthus Items
Karthus Skill Order
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