Ryze Mid Lane is ranked C Tier and has a 45.13% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 12778 Ryze Mid Lane games to compile our statistical Ryze Spellbook Build Guide. For items, our build recommends: Crown of the Shattered Queen, Sorcerer's Shoes, Archangel's Staff, Shadowflame, Cosmic Drive, and Rabadon's Deathcap. For runes, the strongest choice is Sorcery (Primary) with Phase Rush (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Tear of the Goddess, Health Potion, and Stealth Ward. Ryze's Best Spellbook Mid Lane matchups include Rumble, Gwen, and Gangplank. Ryze's Best Spellbook Mid Lane counters are Zyra, Seraphine, and Aatrox.