Vex Mid Lane is ranked S Tier and has a 50.72% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 37483 Vex Mid Lane games to compile our statistical Vex Spellbook Build Guide. For items, our build recommends: Luden's Tempest, Sorcerer's Shoes, Horizon Focus, Shadowflame, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Doran's Ring, Health Potion, and Stealth Ward. Vex's Best Spellbook Mid Lane matchups include Ryze, Twisted Fate, and Ezreal. Vex's Best Spellbook Mid Lane counters are Zilean, Rumble, and Ahri.