Pantheon Mid Lane is ranked A Tier and has a 59.33% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 11182 Pantheon Mid Lane games to compile our statistical Pantheon Spellbook Build Guide. For items, our build recommends: Eclipse, Plated Steelcaps, Youmuu's Ghostblade, Axiom Arc, The Collector, and Black Cleaver. For runes, the strongest choice is Precision (Primary) with Press the Attack (Keystone), and Domination (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Vampiric Scepter, Health Potion, and Stealth Ward. Pantheon's Best Spellbook Mid Lane matchups include Gangplank, Taliyah, and Galio. Pantheon's Best Spellbook Mid Lane counters are Anivia, Gwen, and Varus.