Anivia Mid Lane is ranked A Tier and has a 47.37% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 10525 Anivia Mid Lane games to compile our statistical Anivia Spellbook Build Guide. For items, our build recommends: Liandry's Anguish, Sorcerer's Shoes, Archangel's Staff, Zhonya's Hourglass, Demonic Embrace, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Precision (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Tear of the Goddess, Health Potion, and Stealth Ward. Anivia's Best Spellbook Mid Lane matchups include Azir, Pantheon, and Riven. Anivia's Best Spellbook Mid Lane counters are Wukong, Taliyah, and Zilean.