Nautilus Mid Lane is ranked Off Meta Tier and has a 39.84% win rate in LoL Ultimate Spellbook Patch 11.24. We've analyzed 1049 Nautilus Mid Lane games to compile our statistical Nautilus Spellbook Build Guide. For items, our build recommends: Mercury's Treads, Sunfire Aegis, Winter's Approach, Zhonya's Hourglass, Thornmail, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Amplifying Tome, Doran's Ring, Health Potion, and Stealth Ward. Nautilus's Best Spellbook Mid Lane matchups include Cho'Gath, Akshan, and Anivia. Nautilus's Best Spellbook Mid Lane counters are Twisted Fate, Aurelion Sol, and Syndra.