Lissandra Mid Lane is ranked B Tier and has a 50.65% win rate in LoL Ultimate Spellbook Patch 14.21. We've analyzed 9923 Lissandra Mid Lane games to compile our statistical Lissandra Spellbook Build Guide. For items, our build recommends: Luden's Companion, Malignance, Sorcerer's Shoes, Shadowflame, Zhonya's Hourglass, and Rabadon's Deathcap. For runes, the strongest choice is Domination (Primary) with Electrocute (Keystone), and Sorcery (Secondary). The optimal Summoner Spells for this build are Placeholder and Flash. Starting items should include Boots, Sapphire Crystal, Glowing Mote, Control Ward, and Stealth Ward. Lissandra's Best Spellbook Mid Lane matchups include Karma, Rumble, and Quinn. Lissandra's Best Spellbook Mid Lane counters are Corki, Kennen, and Cho'Gath.
Lissandra Summoner Spells






Lissandra Starting Items










Lissandra Runes
Lissandra Items








Lissandra Skill Order
![]() | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 |
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![]() | Q | Q | Q | Q | Q | |||||||||||||
![]() | W | W | W | W | W | |||||||||||||
![]() | E | E | E | E | E | |||||||||||||
![]() | R | R | R |
Lissandra Item Purchase Order
























Lissandra Ultimate Spellbook Stats
























































































Lissandra Trinkets



Lissandra Boots






Lissandra Situational Items





